sars cov 2 detection kit
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Invitrogen Colorimetric ReadiLAMP™ kit, SARS-CoV-2
- Detection is simple, intuitive and fast: colorimetric LAMP reaction changes color from purple to blue if SARS-target is present. No instrumentation is required for this assay, except for a 65℃ heat source.
- Utilizes non-invasive saliva samples or swab samples
- Ability to detect varying SARS-CoV-2 viral strains
- It can be utilized either of two ways – direct assay using crude samples or assay based on RNA purified from saliva and swabs.
- It allows input of up to 50% purified RNA per LAMP reaction to achieve maximal sensitivity in SARS-CoV-2 detection. See kit performance data.
- Process 1-96 samples at a time: Customers can process more samples with the same number of technicians, using individual tubes, tubes strips, or 96 well plates.
Abstract
In this current pandemic of coronavirus disease 2019 (COVID-19), prompt interventions in terms of early detection and clinical management along with isolation of positive cases is of utmost importance. This helps to limit not only the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections but also the morbidity and mortality associated with it. Different strategies for screening of COVID-19 in containment zones and non-containment areas include testing of symptomatic patients and their contacts in fever clinics, hospital-based testing, testing on demand and population-based screening. The choice of tests like reverse-transcription polymerase chain reaction (RT-PCR), rapid antigen testing (RAT) or antibody test depends upon these strategies and also the turnaround time. Currently, RT-PCR is considered the gold standard for COVID-19 detection. This commentary provides the insights and experiences on COVID-19 diagnosis by RT-PCR. The utility of this test is limited by several false positive, false negative and inconclusive results at early stages of infection, scarcity of reagents and lack of well-equipped labs including trained staff. Moreover, appropriate sample collection and transport, standard laboratory protocols, stringent quality control norms, good quality RNA extraction kits, PCR kits with suitable primers can help in improving accuracy of the test results. A careful assessment of clinical, radiological and molecular findings is required for identifying potential cases of COVID-19.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every corner of the globe, causing societal instability. The resultant coronavirus disease 2019 (COVID-19) leads to fever, sore throat, cough, chest and muscle pain, dyspnoea, confusion, anosmia, ageusia and headache. These can progress to life-threatening respiratory insufficiency, also affecting the heart, kidney, liver and nervous systems. The diagnosis of SARS-CoV-2 infection is often confused with that of influenza and seasonal upper respiratory tract viral infections. Due to available treatment strategies and required containments, rapid diagnosis is mandated. This Review brings clarity to the rapidly growing body of available and in-development diagnostic tests, including nanomaterial-based tools. It serves as a resource guide for scientists, physicians, students and the public at large.
Main
In the span of a few months, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the aetiological agent of coronavirus disease 2019 (COVID-19). Weeks later, viral diagnostic measures were deployed1. This served to supplement the common disease signs and symptoms of COVID-19 of cough, fever and dyspnoea. As all are seen during seasonal upper respiratory tract infections2, precise diagnostic tests detect viral nucleic acids, viral antigens or serological tests are required to affirm SARS-CoV-2 infection3. Chest computed tomography (CT) or magnetic resonance imaging (MRI) confirm disease manifestations2,3. The signature of COVID-19 is the life-threatening acute respiratory distress syndrome (ARDS)4. While the lung is the primary viral target, the cardiovascular, brain, kidney, liver and immune systems are commonly compromised by infection5. Thus, due to significant COVID-19 morbidity and mortality, containment of viral transmission through contact tracing, clinical assessment and virus detection was implemented through social distancing, face masks, contact isolation and hand hygiene to limit SARS-CoV-2 transmission6.
SARS-CoV-2 IgG Detection Kit (Colorimetric Trimer Anti-Spike IgG detection) |
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79975 | BPS Bioscience | 96 rxns. | EUR 765 |
Description: The SARS-CoV-2 IgG detection kit is designed for qualitative detection of human IgG antibodies in serum collected from individuals suspected of prior infection with the virus that causes COVID-19. This fast and simple ELISA uses the trimeric form of the SARS-CoV-2 Spike protein (BPS Bioscience #100728) to identify IgG antibodies that indicate a previous infection with SARS-CoV-2. The Spike protein is expressed on the viral membrane as a trimer, which means this kit measures IgG antibodies in a more physiologically relevant context than many other commercially available ELISA kits. |
SeroFlash SARS-CoV-2 IgM/IgG Antibody Detection Kit |
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D-1001-025 | EpiGentek | 25 tests | EUR 399.3 |
SeroFlash SARS-CoV-2 IgM/IgG Antibody Detection Kit |
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D-1001R-025 | EpiGentek | 25 tests | EUR 399.3 |
SeroFlash SARS-CoV-2 IgM/IgG Antibody Detection Kit |
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D-1001R | EpiGentek | 25 Tests | EUR 377 |
Novel Coronavirus (SARS-CoV-2) Nucleic Acid Detection Kit |
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AGDK-0019 | AcceGen | Kit | Ask for price |
Description: The Novel Coronavirus (SARS-CoV-2) Nucleic Acid Detection Kit is a real-time multiplex RT-PCR test intended for the qualitative detection of SARS-CoV-2 viral RNA. It is suitable for upper respiratory specimens, such as nasopharyngeal, oropharyngeal swab, and bronchoalveolar lavage specimens. In a single RT-PCR reaction, it is able to detect ORF1ab and N RNA sequences, and in addition, human RNase P as an internal control. |
Monoclonal Antibody to SARS-CoV-2 Nucleocapsid Protein (Detection) |
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BSV-COV-AB-34 | BioServUK | 1 mg | EUR 1264 |
Description: Monoclonal Antibody to SARS-CoV-2 Nucleocapsid Protein (Detection) |
Monoclonal Antibody to SARS-CoV-2 Nucleocapsid Protein (Detection) |
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BSV-COV-AB-35 | BioServUK | 1 mg | EUR 1264 |
Description: Monoclonal Antibody to SARS-CoV-2 Nucleocapsid Protein (Detection) |
SARS Protein Detection Set |
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PSI-1810 | ProSci | 1 Set | EUR 884.4 |
Description: A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral S (Spike) protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. The M protein (Membrane protein, Matrix protein) is another major structural viral protein. It is an integral membrane protein involved in the budding of the viral particles and interacts with S protein and the nucleocapsid protein. The SARS E protein contains a short palindromic transmembrane helical hairpin that seems to deform lipid bilayers, which may explain its role in viral budding and virion envelope morphogenesis. ACE2, the SARS receptor, normally plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis.;;For images please see PDF data sheet |
Monoclonal Antibody to SARS-CoV-2 Trimeric Spike Protein, linear epitope (Detection) |
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BSV-COV-AB-32 | BioServUK | 1 mg | EUR 2402 |
Description: Monoclonal Antibody to SARS-CoV-2 Trimeric Spike Protein, linear epitope (Detection) |
Anti-SARS-CoV-2 Antibody IgG Quantitative Detection Kit (Spike RBD) |
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RAS-T049 | ACROBIOSYSTEMS | 96tests | EUR 845.3 |
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective Assay kit detecting the levels of anti-SARS-CoV-2 in human serum can facilitate research on characterization of antibodies produced in response to SARS-CoV-2 infection. |
Anti-SARS-CoV-2 Antibody IgG Quantitative Detection Kit (Spike Trimer) |
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RAS-T048 | ACROBIOSYSTEMS | 96tests | EUR 845.3 |
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective Assay kit detecting the levels of anti-SARS-CoV-2 in human serum can facilitate research on characterization of antibodies produced in response to SARS-CoV-2 infection. |
Anti-SARS-CoV-2 Neutralizing Antibody Quantitative Detection Kit (Spike RBD) |
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RAS-N044 | ACROBIOSYSTEMS | 96tests | EUR 845.3 |
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) poses continual threat to human health due to rapid transmission worldwide.Anti-SARS-CoV-2 Neutralizing Antibody Quantitative Detection Kit (Spike RBD)to test the protective neutralizing antibody levels in post-vaccination serum or convalescent serum. |
Anti-SARS-CoV-2 Antibody IgG Quantitative and Titer Detection Kit (Spike RBD) |
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RAS-T093 | ACROBIOSYSTEMS | 96tests | EUR 845.3 |
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective Assay kit detecting the levels of anti-SARS-CoV-2 in human serum can facilitate research on characterization of antibodies produced in response to SARS-CoV-2 infection. |
Anti-SARS-CoV-2 Antibody IgG Quantitative and Titer Detection Kit (Spike S1) |
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RAS-T095 | ACROBIOSYSTEMS | 96tests | EUR 845.3 |
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective Assay kit detecting the levels of anti-SARS-CoV-2 in human serum can facilitate research on characterization of antibodies produced in response to SARS-CoV-2 infection. |
Anti-SARS-CoV-2 Antibody IgG Quantitative and Titer Detection Kit (Spike Trimer) |
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RAS-T094 | ACROBIOSYSTEMS | 96tests | EUR 845.3 |
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective Assay kit detecting the levels of anti-SARS-CoV-2 in human serum can facilitate research on characterization of antibodies produced in response to SARS-CoV-2 infection. |
COVID19 PCR detection kit |
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BSV-qPCR-07 | BioServUK | 100 reactions | EUR 1201 |
Description: COVID19 PCR detection kit (detecting ORF1ab and N genes of SARS-COV-2 and human gene endogenous control) |
COVID-19 Antigen Detection Kit |
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BSV-G61RHA20 | BioServUK | 20 tests | EUR 500 |
Description: COVID-19 Antigen Detection Kit |
Biocredit Covid-19 Ag Detection Kit |
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G61RHA20 | RapiGEN | 20 test cards (pkg) | EUR 114 |
SEB Detection Kit |
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6030 | Chondrex | 1 kit | EUR 377 |
Description: Liquid Samples |
LPS Detection Kit |
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6039 | Chondrex | 1 kit | EUR 404 |
Description: Serum, Plasma |
DAB Detection Kit |
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E-IR-R101-1mL | Elabscience Biotech | 1mL | EUR 35 |
DAB Detection Kit |
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E-IR-R101-3mL | Elabscience Biotech | 3mL | EUR 50 |
DAB Detection Kit |
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E-IR-R101-6mL | Elabscience Biotech | 6mL | EUR 85 |
DAB Detection Kit |
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E-IR-R101-each | Elabscience Biotech | each | Ask for price |
Fluorocescent Sarcosine Detection Kit |
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SARC100-2 | Cell Technology | 100 Tests | EUR 345 |
HROS Detection Kit |
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FLAPF100-2 | Cell Technology | 150 Tests | EUR 280 |
COVID-19 RT-qPCR Rapid Detection Kit |
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BSV-qPCR-06 | BioServUK | 100 reactions | EUR 695 |
Description: COVID-19 RT-qPCR Rapid Detection Kit |
HMGB1 Detection Kit |
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6010 | Chondrex | 1 kit | EUR 500 |
Description: Serum, Plasma, Culture Media |
DNase Detection Kit |
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PP-410L | Jena Bioscience GmbH | 500reactions | EUR 803.1 |
DNase Detection Kit |
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PP-410S | Jena Bioscience GmbH | 100reactions | EUR 200.8 |
Formaldehyde Detection Kit (2 Plate) |
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K001-F1 | Arbor Assays | 2x96 well plate | EUR 489 |
Description: Formaldehyde Detection assay Kit |
Gliadin Detection Kit |
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6035 | Chondrex | 1 kit | EUR 377 |
Description: Liquid Samples |
Autophagy Detection Kit |
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abx299014-50tests | Abbexa | 50 tests | EUR 627.6 |
Autophagy Detection Kit |
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abx299015-200tests | Abbexa | 200 tests | EUR 1045.2 |
Apoptosis Detection Kit |
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ANXVKB-100T | ImmunoStep | 100 test | EUR 350.9 |
Description: The kit consists of the AnnexinV conjugated in the selected fluorochrome + solution for the exclusion of nonviable cells (PI) and Binding Buffer |
Apoptosis Detection Kit |
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ANXVKCFB-100T | ImmunoStep | 100 test | EUR 306.9 |
Description: The kit consists of the AnnexinV conjugated in the selected fluorochrome + solution for the exclusion of nonviable cells (PI) and Binding Buffer |
Apoptosis Detection Kit |
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ANXVKCFB7-100T | ImmunoStep | 100 test | EUR 306.9 |
Description: The kit consists of the AnnexinV conjugated in the selected fluorochrome + solution for the exclusion of nonviable cells (7AAD) and Binding Buffer |
Apoptosis Detection Kit |
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ANXVKDY-100T | ImmunoStep | 100 test | EUR 287.1 |
Description: The kit consists of the AnnexinV conjugated in the selected fluorochrome + solution for the exclusion of nonviable cells (PI) and Binding Buffer |