sars cov 2 detection kit
Invitrogen Colorimetric ReadiLAMP™ kit, SARS-CoV-2
- Detection is simple, intuitive and fast: colorimetric LAMP reaction changes color from purple to blue if SARS-target is present. No instrumentation is required for this assay, except for a 65℃ heat source.
- Utilizes non-invasive saliva samples or swab samples
- Ability to detect varying SARS-CoV-2 viral strains
- It can be utilized either of two ways – direct assay using crude samples or assay based on RNA purified from saliva and swabs.
- It allows input of up to 50% purified RNA per LAMP reaction to achieve maximal sensitivity in SARS-CoV-2 detection. See kit performance data.
- Process 1-96 samples at a time: Customers can process more samples with the same number of technicians, using individual tubes, tubes strips, or 96 well plates.
Abstract
In this current pandemic of coronavirus disease 2019 (COVID-19), prompt interventions in terms of early detection and clinical management along with isolation of positive cases is of utmost importance. This helps to limit not only the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections but also the morbidity and mortality associated with it. Different strategies for screening of COVID-19 in containment zones and non-containment areas include testing of symptomatic patients and their contacts in fever clinics, hospital-based testing, testing on demand and population-based screening. The choice of tests like reverse-transcription polymerase chain reaction (RT-PCR), rapid antigen testing (RAT) or antibody test depends upon these strategies and also the turnaround time. Currently, RT-PCR is considered the gold standard for COVID-19 detection. This commentary provides the insights and experiences on COVID-19 diagnosis by RT-PCR. The utility of this test is limited by several false positive, false negative and inconclusive results at early stages of infection, scarcity of reagents and lack of well-equipped labs including trained staff. Moreover, appropriate sample collection and transport, standard laboratory protocols, stringent quality control norms, good quality RNA extraction kits, PCR kits with suitable primers can help in improving accuracy of the test results. A careful assessment of clinical, radiological and molecular findings is required for identifying potential cases of COVID-19.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every corner of the globe, causing societal instability. The resultant coronavirus disease 2019 (COVID-19) leads to fever, sore throat, cough, chest and muscle pain, dyspnoea, confusion, anosmia, ageusia and headache. These can progress to life-threatening respiratory insufficiency, also affecting the heart, kidney, liver and nervous systems. The diagnosis of SARS-CoV-2 infection is often confused with that of influenza and seasonal upper respiratory tract viral infections. Due to available treatment strategies and required containments, rapid diagnosis is mandated. This Review brings clarity to the rapidly growing body of available and in-development diagnostic tests, including nanomaterial-based tools. It serves as a resource guide for scientists, physicians, students and the public at large.
Main
In the span of a few months, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the aetiological agent of coronavirus disease 2019 (COVID-19). Weeks later, viral diagnostic measures were deployed1. This served to supplement the common disease signs and symptoms of COVID-19 of cough, fever and dyspnoea. As all are seen during seasonal upper respiratory tract infections2, precise diagnostic tests detect viral nucleic acids, viral antigens or serological tests are required to affirm SARS-CoV-2 infection3. Chest computed tomography (CT) or magnetic resonance imaging (MRI) confirm disease manifestations2,3. The signature of COVID-19 is the life-threatening acute respiratory distress syndrome (ARDS)4. While the lung is the primary viral target, the cardiovascular, brain, kidney, liver and immune systems are commonly compromised by infection5. Thus, due to significant COVID-19 morbidity and mortality, containment of viral transmission through contact tracing, clinical assessment and virus detection was implemented through social distancing, face masks, contact isolation and hand hygiene to limit SARS-CoV-2 transmission6.
 S1 RBD Detection Set) SARS-CoV-2 (COVID-19) S1 RBD Detection Set |
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| SD9400 | ProSci | 1 Set | EUR 569.4 |
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Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6). |
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) SARS-CoV-2 IgG Detection Kit (Colorimetric Anti-Spike RBD IgG detection) |
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| 79985 | BPS Bioscience | 96 rxns. | EUR 590 |
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Description: The SARS-CoV-2 IgG detection kit is designed for qualitative detection of human IgG antibodies in serum collected from individuals suspected of prior infection with the virus that causes COVID-19. This fast and simple ELISA uses the receptor binding domain (RBD) of the SARS-CoV-2 Spike protein (BPS Bioscience #100696) to identify IgG antibodies that indicate a previous infection with SARS-CoV-2. |
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 SARS-CoV-2 Lyophilized Nucleic Acid Detection Kit |
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| TRI-J18S1 | TRI Biotech | 96T | EUR 2381.4 |
SARS-CoV-2 Lyophilized Nucleic Acid Detection Kit |
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| TRI-J18S1S | TRI Biotech | 96T | EUR 2381.4 |
) SARS-CoV-2 IgG Detection Kit (Colorimetric Trimer Anti-Spike IgG detection) |
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| 79975 | BPS Bioscience | 96 rxns. | EUR 765 |
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Description: The SARS-CoV-2 IgG detection kit is designed for qualitative detection of human IgG antibodies in serum collected from individuals suspected of prior infection with the virus that causes COVID-19. This fast and simple ELISA uses the trimeric form of the SARS-CoV-2 Spike protein (BPS Bioscience #100728) to identify IgG antibodies that indicate a previous infection with SARS-CoV-2. The Spike protein is expressed on the viral membrane as a trimer, which means this kit measures IgG antibodies in a more physiologically relevant context than many other commercially available ELISA kits. |
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 SeroFlash SARS-CoV-2 IgM/IgG Antibody Detection Kit |
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| D-1001-025 | EpiGentek | 25 tests | EUR 399.3 |
SeroFlash SARS-CoV-2 IgM/IgG Antibody Detection Kit |
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| D-1001R | EpiGentek | 25 Tests | EUR 69 |
SeroFlash SARS-CoV-2 IgM/IgG Antibody Detection Kit |
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| D-1001R-025 | EpiGentek | 25 tests | EUR 399.3 |
 Nucleic Acid Detection Kit) Novel Coronavirus (SARS-CoV-2) Nucleic Acid Detection Kit |
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| AGDK-0019 | AcceGen | Kit | Ask for price |
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Description: The Novel Coronavirus (SARS-CoV-2) Nucleic Acid Detection Kit is a real-time multiplex RT-PCR test intended for the qualitative detection of SARS-CoV-2 viral RNA. It is suitable for upper respiratory specimens, such as nasopharyngeal, oropharyngeal swab, and bronchoalveolar lavage specimens. In a single RT-PCR reaction, it is able to detect ORF1ab and N RNA sequences, and in addition, human RNase P as an internal control. |
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 RNA) SARS-CoV-2 Real-TM Real Time PCR kit for detection of SARS-CoV2 (COVID19) RNA |
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| V435-100FRT | Sacace Biotechnologies | 96 | EUR 1046.4 |
) SARS-COV-2 Nucleic Acid Detection Kit (Fluorescence RT-PCR) |
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| TRI-J16L1 | TRI Biotech | 500T | EUR 12247.2 |
SARS-COV-2 Nucleic Acid Detection Kit (Fluorescence RT-PCR) |
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| TRI-J16M1 | TRI Biotech | 48T | EUR 1638 |
SARS-COV-2 Nucleic Acid Detection Kit (Fluorescence RT-PCR) |
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| TRI-J16S1 | TRI Biotech | 24T | EUR 831.6 |
) Recombinant SARS-Cov-2 Spike RBD Protein (Detection) |
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| MBS355895-1mg | MyBiosource | 1mg | EUR 885 |
Recombinant SARS-Cov-2 Spike RBD Protein (Detection) |
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| MBS355895-5x1mg | MyBiosource | 5x1mg | EUR 3690 |
) SARS-CoV-2 Nucleic Acid Rapid Detection Kit (Fluorescence RT-PCR) |
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| TRI-J21M1 | TRI Biotech | 48T | EUR 982.8 |
SARS-CoV-2 Nucleic Acid Rapid Detection Kit (Fluorescence RT-PCR) |
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| TRI-J21M1A | TRI Biotech | 48T | EUR 982.8 |
SARS-CoV-2 Nucleic Acid Rapid Detection Kit (Fluorescence RT-PCR) |
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| TRI-J21S1 | TRI Biotech | 24T | EUR 504 |
SARS-CoV-2 Nucleic Acid Rapid Detection Kit (Fluorescence RT-PCR) |
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| TRI-J21S1A | TRI Biotech | 24T | EUR 504 |
 uncut sheet of SARS-CoV-2 IgG detection kit（colloidal gold method） |
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| E42020TDB4 | EnoGene | / | EUR 276.5 |
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Description: / |
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 uncut sheet of SARS-CoV-2 IgM detection kit（colloidal gold method） |
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| E42020TDB5 | EnoGene | / | EUR 276.5 |
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Description: / |
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) uncut sheet of SARS-CoV-2 IgG detection kit (colloidal gold method) |
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| MBS8584979-1Sheet | MyBiosource | 1Sheet | EUR 475 |
uncut sheet of SARS-CoV-2 IgG detection kit (colloidal gold method) |
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| MBS8584979-5Sheets | MyBiosource | 5Sheets | EUR 1985 |
) uncut sheet of SARS-CoV-2 IgM detection kit (colloidal gold method) |
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| MBS8584980-1Sheet | MyBiosource | 1Sheet | EUR 475 |
uncut sheet of SARS-CoV-2 IgM detection kit (colloidal gold method) |
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| MBS8584980-5Sheets | MyBiosource | 5Sheets | EUR 1985 |
) SARS-CoV-2 Nucleic Acid Multiple Rapid Detection Kit(Fluorescent RT-PCR) |
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| TRI-J25M1 | TRI Biotech | 48T | EUR 1063.44 |
SARS-CoV-2 Nucleic Acid Multiple Rapid Detection Kit(Fluorescent RT-PCR) |
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| TRI-J25S1 | TRI Biotech | 24T | EUR 549.36 |
, Influenza A&B) SARS-CoV-2/Influenza A/B Real-TM RT PCR kit for detection of SARS-CoV2 (COVID19), Influenza A&B |
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| V440-100FRT | Sacace Biotechnologies | 96 | EUR 1046.4 |
 uncut sheet of SARS-CoV-2 IgM/IgG detection kit（colloidal gold method） |
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| E42020TDB6 | EnoGene | / | EUR 276.5 |
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Description: / |
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) uncut sheet of SARS-CoV-2 IgM/IgG detection kit (colloidal gold method) |
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| MBS8584981-1Sheet | MyBiosource | 1Sheet | EUR 475 |
uncut sheet of SARS-CoV-2 IgM/IgG detection kit (colloidal gold method) |
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| MBS8584981-5Sheets | MyBiosource | 5Sheets | EUR 1985 |
) Monoclonal Antibody to SARS-CoV-2 Nucleocapsid Protein (Detection) |
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| BSV-COV-AB-34 | BioServUK | 1 mg | EUR 1264 |
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Description: Monoclonal Antibody to SARS-CoV-2 Nucleocapsid Protein (Detection) |
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Monoclonal Antibody to SARS-CoV-2 Nucleocapsid Protein (Detection) |
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| BSV-COV-AB-35 | BioServUK | 1 mg | EUR 1264 |
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Description: Monoclonal Antibody to SARS-CoV-2 Nucleocapsid Protein (Detection) |
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) SARS-CoV-2 B.1.351 Variant Nucleic Acid Detection Kit (Fluorescence RT-PCR) |
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| TRI-J20M1 | TRI Biotech | 48T | EUR 1638 |
) SARS-CoV-2 B.1.1.7 Variant Nucleic Acid Detection Kit (Fluorescence RT-PCR) |
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| TRI-J19M1 | TRI Biotech | 48T | EUR 1638 |
 uncut sheet of SARS-CoV-2 neutralizing antibody detection kit（colloidal gold method） |
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| E42020TDB3 | EnoGene | double-antigen-sandwich-method(can-ignore-non-neutralizing-antibody) | EUR 276.5 |
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Description: double antigen sandwich method（can ignore non neutralizing antibody） |
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) uncut sheet of SARS-CoV-2 neutralizing antibody detection kit (colloidal gold method) |
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| MBS8584978-1Sheet | MyBiosource | 1Sheet | EUR 475 |
uncut sheet of SARS-CoV-2 neutralizing antibody detection kit (colloidal gold method) |
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| MBS8584978-5Sheets | MyBiosource | 5Sheets | EUR 1985 |
